HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 1,1-Dicyclohexyl-3-(4-morpholin-4-ylmethyl-thiazol-2-yl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 1,1-Dicyclohexyl-3-(4-formyl-thiazol-2-yl)urea | HCID 57883668 | — |
| Product | 1,1-Dicyclohexyl-3-(4-morpholin-4-ylmethyl-thiazol-2-yl)urea | HCID 57883946 | 30% |
Reaction Steps
1,1-Dicyclohexyl-3-(4-morpholin-4-ylmethyl-thiazol-2-yl)-urea was prepared in 30% yield (30 mg) as described in general procedure A from 1,1-dicyclohexyl-3-(4-formyl-thiazol-2-yl)-urea (101 mg, 0.3 mmol) and morpholine (30 μL, 0.3 mmol) using sodium triacetoxyborohydride as the reducing reagent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07598391B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-a5a429b8da82420487e721744617c9f6 |
| Source note | uspto-grants-2009_10 |