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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1818391Generated: November 2, 2026

Dithioerythritol → 1-(1-Acetyl-piperidin-4-yl)-3-[5-(2-azepan-1-yl-ethylsulfanyl)-thiazol-2-yl]-1-cyclohexyl urea

https://huagongshe.com/reaction/1818391

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDithioerythritolHCID 439352—
Reactant2-(Hexamethyleneimino)ethyl chlorideHCID 53445278—
Reactant1-(1-Acetyl-piperidin-4-yl)-1-cyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-ureaHCID 86611190—
Product1-(1-Acetyl-piperidin-4-yl)-3-[5-(2-azepan-1-yl-ethylsulfanyl)-thiazol-2-yl]-1-cyclohexyl ureaHCID 57883731—

Reaction Steps

Prepared as described in general procedures (H) and (i) using 1-(1-acetyl-piperidin-4-yl)-1-cyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and 2-(hexamethyleneimino)ethylchloride

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598391B2
Source datasetuspto-grants-2009_10
ORD IDord-5197b5db8e7442faa3a68e01187dcb8c
Source noteuspto-grants-2009_10