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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1818402Generated: October 30, 2026

1-acetyl-N-(4-methylcyclohexyl)piperidin-4-amine → HCID 178473844, compound

https://huagongshe.com/reaction/1818402

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-acetyl-N-(4-methylcyclohexyl)piperidin-4-amineHCID 25219596—
ReactantEthyl 3-[(2-amino-1,3-thiazol-5-YL)sulfanyl]propanoateHCID 57481428—
Reactant3-{2-[3-(1-Acetyl-piperidin-4-yl)-3-(4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-propionic acid ethyl esterHCID 86611221—
ProductHCID 178473844HCID 178473844—

Reaction Steps

3-{2-[3-(1-Acetyl-piperidin-4-yl)-3-(4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-propionic acid ethyl ester prepared as described in general procedures (A) and (B) using 1-[4-(4-methyl-cyclohexylamino)-piperidin-1-yl]-ethanone and 3-(2-amino-thiazol-5-ylsulfanyl)-propionic acid ethyl ester. Hydrolysis using general procedure (F) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07598391B2
Source datasetuspto-grants-2009_10
ORD IDord-031940fa02c54b1f9ca07dab5315b924
Source noteuspto-grants-2009_10