HuagongsheHuagongshe Chemistry Print Report · For research reference only
alpha-Hydroxyacetophenone → 1-Phenyl-1,2-ethanediol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | alpha-Hydroxyacetophenone | HCID 68490 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Product | 1-Phenyl-1,2-ethanediol | HCID 7149 | 98% |
Reaction Steps
The reaction of α-hydroxyacetophenone was performed by the same method as in Example 3 except that the reaction was performed at a hydrogen pressure of 10 atm. As a result, optically active 1-phenyl-1,2-ethanediol with 97% ee was produced in a yield of 98%. The R and S isomers were not identified.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601667B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-15d9a5c2c69b48e89e02334292139a8f |
| Source note | uspto-grants-2009_10 |