HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylcyclopropane-1-sulfonamide → 1-Benzoylcyclopropane-1-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylcyclopropane-1-sulfonamide | HCID 21889814 | — |
| Reactant | 1-Benzoyl-N-tert-butylcyclopropane-1-sulfonamide | HCID 21889830 | — |
| Product | 1-Benzoylcyclopropane-1-sulfonamide | HCID 21889794 | 87% |
Reaction Steps
This compound was obtained in 87% yield from N-tert-butyl(1-benzoyl)cyclopropyl-sulfonamide (from Step A.6.a) using the procedure described for the synthesis of 1-methylcyclopropylsulfonamide, followed by recrystallization from the minimum amount of ethyl acetate in hexane: 1H NMR (DMSO-d6) δ 1.39 (m, 2H), 1.61 (m, 2H), 7.22 (s, 2H), 7.53 (t, J=7.6 Hz, 2H), 7.65 (t, J=7.6 Hz, 1H), 8.06 (d, J=8.2 Hz, 2H); 13C NMR (DMSO-d6) δ 12.3, 48.4, 128.1, 130.0, 133.4, 135.3, 192.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601686B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-61e95e15f103478c8136d56a7e741f41 |
| Source note | uspto-grants-2009_10 |