1-(4-Aminophenoxy)-3-(dimethylamino)propan-2-ol → 2-[4-(3-Dimethylamino-2-hydroxy-propoxy)-phenylamino]-8-indan-5-yl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid ethyl ester
Reaction equation
[CH2:16]([CH3:17])[O:18][C:19](=[O:20])[c:21]1[c:22](=[O:44])[c:23]2[c:24]([n:25][c:26]([S:29]([CH3:30])(=[O:31])=[O:32])[n:27][cH:28]2)[n:33](-[c:35]2[cH:36][c:37]3[c:41]([cH:42][cH:43]2)[CH2:40][CH2:39][CH2:38]3)[cH:34]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH2:7][CH:8]([CH2:9][N:10]([CH3:11])[CH3:12])[OH:13])[cH:14][cH:15]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([O:6][CH2:7][CH:8]([CH2:9][N:10]([CH3:11])[CH3:12])[OH:13])[cH:14][cH:15]1)[c:26]1[n:25][c:24]2[c:23]([c:22](=[O:44])[c:21]([C:19]([O:18][CH2:16][CH3:17])=[O:20])[cH:34][n:33]2-[c:35]2[cH:36][c:37]3[c:41]([cH:42][cH:43]2)[CH2:40][CH2:39][CH2:38]3)[cH:28][n:27]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-c712768e53a046bcba99d03969be4bc4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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