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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1819159Generated: October 26, 2026

2,2-Diphenylethylamine → 3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}-N-(2,2-diphenylethyl)benzamide

https://huagongshe.com/reaction/1819159

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-DiphenylethylamineHCID 77575—
Reactant3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acidHCID 58327807—
Product3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}-N-(2,2-diphenylethyl)benzamideHCID 67091428—

Reaction Steps

3-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 2,2-diphenylethylamine as in General Procedure 10 to give the title compound. LCMS: m/z=626.96 (M+H+); retention time=1.06 minutes.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07601716B2
Source datasetuspto-grants-2009_10
ORD IDord-0e3f2d8cd2c745758fda443a10a7169e
Source noteuspto-grants-2009_10