HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Pyrrolidin-2-yl)pyridine → (3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-(2-pyridin-3-ylpyrrolidin-1-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Pyrrolidin-2-yl)pyridine | HCID 412 | — |
| Reactant | 3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid | HCID 58327807 | — |
| Product | (3-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-(2-pyridin-3-ylpyrrolidin-1-yl)methanone | HCID 58327923 | — |
Reaction Steps
3-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 2-(3-pyridinyl)pyrrolidine as in General Procedure 10 to give the title compound. LCMS: m/z=577.95 (M+H+); retention time=0.65 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601716B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-5b2f0383f4a54ebfb0275c8d80101740 |
| Source note | uspto-grants-2009_10 |