HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-(Trifluoromethyl)phenyl)piperazine → (4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-(Trifluoromethyl)phenyl)piperazine | HCID 4296 | — |
| Reactant | 4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid | HCID 46906718 | — |
| Product | (4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}methanone | HCID 58327800 | — |
Reaction Steps
4-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 1-[3-(trifluoromethyl)phenyl]piperazine as in General Procedure 10 to give the title compound. LCMS: m/z=659.99 (M+H+); retention time=1.08 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601716B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-f42f1f01a67a4667b8c688321eb15111 |
| Source note | uspto-grants-2009_10 |