HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperazin-1-yl)furo[3,2-c]pyridine → (4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-(4-furo[3,2-c]pyridin-4-ylpiperazin-1-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperazin-1-yl)furo[3,2-c]pyridine | HCID 2794808 | — |
| Reactant | 4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid | HCID 46906718 | — |
| Product | (4-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}phenyl)-(4-furo[3,2-c]pyridin-4-ylpiperazin-1-yl)methanone | HCID 58327808 | — |
Reaction Steps
4-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 1-(4-furo[3,2-c]pyridinyl)piperazine as in General Procedure 10 to give the title compound. LCMS: m/z=633.03 (M+H+); retention time=0.63 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601716B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-5d66fd5aca1047b681e15ca17385fc42 |
| Source note | uspto-grants-2009_10 |