HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 1-(5-Amino-2-hydroxyphenyl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-(3-Acetyl-4-hydroxyphenyl)acetamide | HCID 81720 | — |
| Product | 1-(5-Amino-2-hydroxyphenyl)ethanone | HCID 2775222 | — |
Reaction Steps
A suspension of N-(3-acetyl-4-hydroxy-phenyl)-acetamide (1.029 g, 5.3 mmol) in 15% HCl (1.5 ml, 6.2 mmol, 1.2 equ) was heated to reflux for 40 minutes, then cooled and neutralised with 10% aqueous ammonia. The precipitated solid was collected by filtration as 1-(5-amino-2-hydroxy-phenyl)-ethanone (0.677 g, 84%) a green solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601754B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-2ed52949da7949a6977a868312158493 |
| Source note | uspto-grants-2009_10 |