HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isoxazole, 4-(chloromethyl)-5-methyl-3-phenyl- → {2-Methyl-3-[2-(5-methyl-3-phenyl-isoxazol-4-ylmethyl)-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-indol-1-yl}-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isoxazole, 4-(chloromethyl)-5-methyl-3-phenyl- | HCID 11052826 | — |
| Reactant | [3-(1,1-Dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl)-2-methyl-indol-1-yl]-acetic acid tert-butyl ester | HCID 67317115 | — |
| Product | {2-Methyl-3-[2-(5-methyl-3-phenyl-isoxazol-4-ylmethyl)-1,1-dioxo-2,3-dihydro-1h-1lambda6-benzo[d]isothiazol-3-yl]-indol-1-yl}-acetic acid | HCID 11526569 | — |
Reaction Steps
The title compound was prepared by the method described for example 14 using the product from example 3, step c) and 4-chloromethyl-5-methyl-3-phenyl-isoxazole. MS: ESI (negative): 526 (M−H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601749B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-045b3733abc744098149802e8ba7794e |
| Source note | uspto-grants-2009_10 |