HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1-methyl-1H-indol-3-yl)acetic acid → HCID 178480349, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1-methyl-1H-indol-3-yl)acetic acid | HCID 254166 | — |
| Reactant | 4-Amino-3,5-dichlorobenzylamine | HCID 18975763 | — |
| Reactant | HCID 178488081 | HCID 178488081 | — |
| Product | HCID 178480349 | HCID 178480349 | — |
Reaction Steps
In a manner similar to that used in the preparation of the compound of example 2, but using 2-(1-methyl-1H-indol-3-yl)acetic acid in step 5 (A) and 3,5-dichloro-4-aminobenzylamine (preparation A) in step 5 (B), the title compound was prepared. MS (ESI) (M+H)+=404.07 1H-NMR(500 MHz, CD3OD) δ 7.54 (d, J=7.93 Hz, 1 H), 7.40 (d, J=8.24 Hz, 1 H), 7.15-7.32 (m, 4 H), 7.04-7.15 (m, 1 H), 4.33 (s, 2 H), 3.95 (s, 2 H), 3.80 (s, 3 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601751B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-ebc3a16afffd4a18aabbb14790e23966 |
| Source note | uspto-grants-2009_10 |