HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1H-indol-3-yl)propanoic acid → HCID 178460304, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1H-indol-3-yl)propanoic acid | HCID 10899423 | — |
| Reactant | 4-Amino-3,5-dichlorobenzylamine | HCID 18975763 | — |
| Reactant | HCID 178488081 | HCID 178488081 | — |
| Product | HCID 178460304 | HCID 178460304 | — |
Reaction Steps
In a manner similar to that used in the preparation of the compound of example 2, but using 2-(1H-indol-3-yl)propionic acid in step 8 (A) and 3,5-dichloro-4-aminobenzylamine (preparation A) in step 8 (B), the title compound was prepared. MS (ESI) (M+H)+=404.03 1H-NMR (500 MHz, CD3OD) δ 7.55 (d, J=7.93 Hz, 1 H), 7.40 (d, J=7.93 Hz, 1 H), 7.28 (s, 1 H), 7.19 (s, 2 H), 7.12-7.17 (m, 1 H), 7.02-7.08 (m, 1 H), 4.31 (s, 2 H), 4.14 (m, 1 H), 1.63 (d, J=7.02 Hz, 3 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601751B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-c7720a3295804faa9e17916be46b41fe |
| Source note | uspto-grants-2009_10 |