5-Hydroxyindoleacetic Acid → HCID 178474309, compound

Participants

Reaction Steps

In a manner similar to that used in the preparation of the compound of example 2, but using 2-(5-hydroxy-1H-indol-3-yl)acetic acid in step 14 (A) and 4-acetamido-3,5-dichloro-benzylamine (preparation B) in step 14 (B), the title compound was prepared. MS (ESI) (M+H)+=448.05 1H-NMR (500 MHz, CD3OD) δ 7.41 (s, 2 H), 7.15-7.30 (m, 2 H), 6.93 (d, J=2.44 Hz, 1 H), 6.73 (dd, J=8.70, 2.29 Hz, 1 H), 4.47 (s, 2 H), 3.88 (s, 2 H), 2.19 (s, 3 H).

Provenance & Evidence