HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Fluoroindole-3-acetic acid → HCID 178474310, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Fluoroindole-3-acetic acid | HCID 2774507 | — |
| Reactant | N-(4-(aminomethyl)-2,6-dichlorophenyl)acetamide | HCID 58962993 | — |
| Reactant | HCID 178488081 | HCID 178488081 | — |
| Product | HCID 178474310 | HCID 178474310 | — |
Reaction Steps
In a manner similar to that used in the preparation of the compound of example 2, but using 2-(6-fluoro-1H-indol-3-yl)acetic acid in step 16 (A) and 4-acetamido-3,5-dichloro-benzylamine (preparation B) in step 16 (B), the title compound was prepared. MS (ESI) (M+H)+=450.08 1H-NMR(500 MHz, CD3OD) δ 7.52 (dd, J=8.55, 5.19 Hz, 1 H), 7.42 (s, 2 H), 7.28 (s, 1 H), 7.09 (dd, J=9.77, 2.14 Hz, 1 H), 6.77-6.95 (m, 1 H), 4.50 (s, 2 H), 3.95 (s, 2 H), 2.19 (s, 3 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601751B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-2e6c6b1a26f84f2ba54542c8bba57d37 |
| Source note | uspto-grants-2009_10 |