2-Bromo-4'-methylacetophenone → HCID 11676202, compound

HRID 1819738Notes

Reaction equation

HRID 1819738 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][CH:6]=1)=O.[NH2:12][C:13]1[S:14][C:15]2[CH:21]=[C:20]([Br:22])[CH:19]=[CH:18][C:16]=2[N:17]=1>>[BrH:1].[Br:22][C:20]1[CH:19]=[CH:18][C:16]2[N:17]3[CH:2]=[C:3]([C:5]4[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][CH:6]=4)[N:12]=[C:13]3[S:14][C:15]=2[CH:21]=1

Participants

3

Reactant 2

HCID 692722-Bromo-4'-methylacetophenoneHCID 851492-Benzothiazolamine, 6-bromo-

Product 1

HCID 11676202HCID 11676202, compoundYield 24%

Procedure

The title compound is prepared from 2-bromo-4′-methylacetophenone and 2-amino-6-bromobenzothiazole using method B in 24% yield: mp 205-208° C.; 1H-NMR (DMSO-d6) 2.31 (s, 3H), 7.23 (d, 2H), 7.73 (m, 3H), 7.91 (d, 1H), 8.32 (s, 1H), 8.70 (s, 1H); HR-MS (EI) m/z 341.9822 (M+).

Sources & evidence

ORD record
ord-6ecf942fac9748a0bce4951a060866c8
Source dataset
uspto-grants-2009_10
Patent number
US07601846B2

Reaction notes

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