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HRID1819739

反应详情

EQUATION

反应方程式

HRID 1819739 的结构方程式

REACTANTS

反应物

2
结构：Nc1nc2ccccc2s1
HCID8706

2-Aminobenzothiazole

C7H6N2S

结构：O=C(CBr)c1ccc(N2CCCC2)cc1
HCID3681785

2-Bromo-1-[4-(pyrrolidin-1-yl)phenyl]ethan-1-one

C12H14BrNO

PRODUCTS

生成物

1
结构：Br.c1ccc2c(c1)sc1nc(-c3ccc(N4CCCC4)cc3)cn12
HCID11509559

未命名化合物

收率 16%

PROCEDURE

实验过程

The title compound is prepared from α-bromo-4-(1-pyrrolidino)acetophenone (Lancaster) and 2-aminobenzothiazole using method B and 10 hours of reflux in 16% yield: mp 283-287° C.; 1H-NMR (DMSO-d6) 1.98 (m, 4H), 3.31 (m, 4H), 6.68 (m, 2H), 7.51 (d, 1H), 7.66 (d, 3H), 8.11 (m, 2H), 8.71 (s, 1H); Anal. (C19H18BrN3S) C, H, N.

WORKUP

后处理

  1. temperatureof reflux in 16% yield