HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Amino-2,6-dichlorophenol → 3,5-Dichloro-4-(4-methoxy-benzothiazol-2-yloxy)-phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Amino-2,6-dichlorophenol | HCID 80037 | — |
| Reactant | 2-Chloro-4-methoxy-1,3-benzothiazole | HCID 2049862 | — |
| Product | 3,5-Dichloro-4-(4-methoxy-benzothiazol-2-yloxy)-phenylamine | HCID 18511500 | — |
Reaction Steps
3,5-Dichloro-4-(4-methoxy-benzothiazol-2-yloxy)-phenylamine was synthesized (21%) from 2-chloro-4-methoxybenzotiazole (257) and 4-amino-2,6-dichlorophenol (Aldrich) in a similar manner as described in Example 417. 1H NMR (400 MHz, DMSO-d6) δ 7.48 (d, J=8.0 Hz, 1H), 7.28 (t, J=8.1 Hz, 1H), 7.01 (d, J=8.1 Hz, 1H), 6.73 (s, 2H), 5.86 (s, 2H), 3.85 (s, 3H). MS (EI): m/z 341 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601841B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-eff893d5539745679417245eb539ad00 |
| Source note | uspto-grants-2009_10 |