2-Chloro-1,3-thiazole-5-sulfonamide → 2-[7-Trifluoromethyl-5-(3-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiazole-5-sulfonic acid amide

HRID 181981Notes

Reaction equation

HRID 181981 reaction equation
[C:1](#[CH:2])[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][c:18]([C:22]([F:23])([F:24])[F:25])[cH:19][cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15].[Cl:26][c:27]1[s:28][c:29]([S:32](=[O:33])(=[O:34])[NH2:35])[cH:30][n:31]1>>[C:1](#[C:2][c:27]1[s:28][c:29]([S:32](=[O:33])(=[O:34])[NH2:35])[cH:30][n:31]1)[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][c:18]([C:22]([F:23])([F:24])[F:25])[cH:19][cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15]

Participants

3

Reactant 2

HCID 220195182-Chloro-1,3-thiazole-5-sulfonamideHCID 866080553-Ethynyl-7-trifluoromethyl-5-(3-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 866080562-[7-Trifluoromethyl-5-(3-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiazole-5-sulfonic acid amide

Sources & evidence

ORD record
ord-7322fb55574d49babb659874cf68982e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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