Triethylamine → HCID 24899192, compound

Participants

Reaction Steps

Following the procedure for Example 1, tetrahydro-dibenzofuran-2-ylamine (1.1 g, 6.0 mmol), isovaleryl chloride (0.82 g, 6.6 mmol), and triethylamine (2.6 mL, 18 mmol) in tetrahydrofuran (11 mL) provided 3-methyl-N-(6,7,8,9-tetrahydro-dibenzofuran-2-yl)-butyramide (0.69 g) after recrystallization from t-butyl methyl ether. Mp 154-157° C.; Anal. Calcd. for C17H21NO2: C, 75.25; H, 7.80; N, 5.16; Found: C, 75.20; H, 7.87; N, 5.26.

Provenance & Evidence