HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 5305518, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 4-(Trifluoromethyl)benzoyl chloride | HCID 67607 | — |
| Reactant | HCID 21221605 | HCID 21221605 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 5305518 | HCID 5305518 | 57.8% |
Reaction Steps
Following the procedure of Example 1, tetrahydro-dibenzofuran-2-ylamine (1.0 g, 5.3 mmol), 4-(trifluoromethyl)benzoyl chloride (0.79 mL, 5.3 mmol), and pyridine (1.1 mL, 13 mmol) in acetonitrile (50 mL) provided N-(6,7,8,9-tetrahydrodibenzo[b,d]furan-2-yl)-4-(trifluoromethyl)benzamide (1.1 g). MS (ESI) m/z 358 ([M−H]); m/z 360 ([M+H]+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601856B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-ee5f3e7d53db4218bfb73a8f03f79e84 |
| Source note | uspto-grants-2009_10 |