3,3-Dimethylbutanoyl chloride → HCID 24899954, compound

Participants

Reaction Steps

Following the procedure of Example 1, 7,8,9,10-tetrahydro-6H-benzo[b]-cyclohepta[d]furan-2-ylamine (1.0 g, 5.0 mmol) and t-butylacetyl chloride (0.74 mL, 5.5 mmol) in pyridine (10 mL) provided 3,3-dimethyl-N-[7,8,9,10-tetrahydro-6H-benzo[b]-cyclohepta[d]furan-2-yl]butyramide (0.92 g). Mp 182-183° C.; Anal. Calcd. for C19H25NO2: C, 76.22; H, 8.42; N, 4.68; Found: C, 76.13; H, 8.28; N, 4.71.

Provenance & Evidence