Benzo-1,3-dioxole-5-methylamine → HCID 51301811, compound

HRID 1819990Notes

Reaction equation

HRID 1819990 reaction equation
[CH2:1]1[O:11][C:10]2[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][C:3]=2[O:2]1.[CH2:12]1[O:20][C:19]2[CH:18]=[CH:17][C:16]([N:21]=[C:22]=[O:23])=[CH:15][C:14]=2[O:13]1>C1C=CC=CC=1>[CH2:12]1[O:20][C:19]2[CH:18]=[CH:17][C:16]([NH:21][C:22]([NH:7][CH2:6][C:5]3[CH:8]=[CH:9][C:10]4[O:11][CH2:1][O:2][C:3]=4[CH:4]=3)=[O:23])=[CH:15][C:14]=2[O:13]1

Participants

4

Reactant 2

HCID 75799Benzo-1,3-dioxole-5-methylamineHCID 52232135-Isocyanato-1,3-dioxaindane

Product 1

HCID 51301811HCID 51301811, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A solution of 3,4-methylenedioxybenzylamine (0.37 g) and 3,4-methylenedioxyphenyl isocyanate (0.4 g) in benzene (25 ml) was refluxed for 1 hour. The precipitate formed was filtered, washed with benzene then dried to give pure DC-0077B (0.78 g, 98%) as a pale brown solid.

Workup

  1. customThe precipitate formed
  2. filtrationwas filtered
  3. washwashed with benzene
  4. customthen dried
  5. customto give pure DC-0077B (0.78 g, 98%) as a pale brown solid

Sources & evidence

ORD record
ord-abe9c39036564f928897e740c0cdbdfe
Source dataset
uspto-grants-2009_10
Patent number
US07601876B2

Reaction notes

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