tert-butyl N-(2-hydroxyethyl)carbamate → 2,3,3a,4,5,6a-Hexahydrofuro[2,3-b]furan-4-yl 5-[[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]methyl]-2,2-dimethyl-4-[[4-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]phenyl]methyl]-1,3-oxazolidine-3-carboxylate

HRID 182015Notes

Reaction equation

HRID 182015 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][CH2:10][OH:11].[O:12]1[CH2:13][O:14][c:15]2[c:16]1[cH:17][cH:18][c:19]([S:21](=[O:22])(=[O:23])[N:24]([CH2:25][CH:26]([CH3:27])[CH3:28])[CH2:29][CH:30]1[CH:31]([CH2:48][c:49]3[cH:50][cH:51][c:52]([OH:55])[cH:53][cH:54]3)[N:32]([C:37](=[O:38])[O:39][CH:40]3[CH2:41][O:42][CH:43]4[O:44][CH2:45][CH2:46][CH:47]34)[C:33]([CH3:35])([CH3:36])[O:34]1)[cH:20]2>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH2:9][CH2:10][O:11][c:52]1[cH:51][cH:50][c:49]([CH2:48][CH:31]2[CH:30]([CH2:29][N:24]([S:21]([c:19]3[cH:18][cH:17][c:16]4[c:15]([cH:20]3)[O:14][CH2:13][O:12]4)(=[O:22])=[O:23])[CH2:25][CH:26]([CH3:27])[CH3:28])[O:34][C:33]([CH3:35])([CH3:36])[N:32]2[C:37](=[O:38])[O:39][CH:40]2[CH2:41][O:42][CH:43]3[O:44][CH2:45][CH2:46][CH:47]23)[cH:54][cH:53]1

Participants

3

Reactant 2

HCID 2733206tert-butyl N-(2-hydroxyethyl)carbamateHCID 207741912,3,3a,4,5,6a-Hexahydrofuro[2,3-b]furan-4-yl 5-[[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]methyl]-4-[(4-hydroxyphenyl)methyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

Product 1

HCID 207741842,3,3a,4,5,6a-Hexahydrofuro[2,3-b]furan-4-yl 5-[[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]methyl]-2,2-dimethyl-4-[[4-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]phenyl]methyl]-1,3-oxazolidine-3-carboxylate

Sources & evidence

ORD record
ord-fd326177e7e8404bac8ac7ca92cc73bc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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