HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Chlorophenyl)-4-hydroxypiperidine → N-(1-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)-4-methyl-1-oxopentan-2-yl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Chlorophenyl)-4-hydroxypiperidine | HCID 38282 | — |
| Reactant | 3-Methyl-2-(phenylformamido)butanoic acid | HCID 226682 | — |
| Reactant | N-Benzoyl-DL-leucine | HCID 294887 | — |
| Reactant | 4-(4-chlorophenyl)piperidine Hydrochloride | HCID 2757843 | — |
| Product | N-(1-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)-4-methyl-1-oxopentan-2-yl)benzamide | HCID 57889972 | — |
Reaction Steps
Example 215 was prepared in a similar manner as described for the preparation of Example 208 with the exceptions that benzoyl-DL-leucine and 4-(4-chlorophenyl)-4-hydroxypiperidine were substituted for benzoyl-DL-valine and 4-(4-chlorophenyl)piperidine hydrochloride, respectively. MS found: (M+H)+=430.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601844B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-ef3917b846884793aae18eb0ffbcfcf1 |
| Source note | uspto-grants-2009_10 |