HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Acetoxybenzoic acid → HCID 67300177, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Acetoxybenzoic acid | HCID 238669 | — |
| Reactant | HCID 67299489 | HCID 67299489 | — |
| Product | HCID 67300177 | HCID 67300177 | 50% |
Reaction Steps
(R)-2-Amino-1-(4-(4-chlorophenyl)piperidin-1-yl)-3-methylbutan-1-one hydrochloride was coupled with 3-acetoxy benzoic acid in a similar manner as described for the preparation of Example 75 to give (R)-3-((1-(4-(4-chlorophenyl)piperidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamoyl)phenyl acetate (115 mg, 50% yield). MS found: 457.3 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601844B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-9162ceeda8d64d21baf0f4409aa6000c |
| Source note | uspto-grants-2009_10 |