HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Cyclobutylpiperazine → HCID 24756897, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Cyclobutylpiperazine | HCID 4738602 | — |
| Reactant | 2-(Morpholine-4-carbonyl)-1-(2,2,2-trifluoro-ethyl)-1H-indole-5-carboxylic acid | HCID 68681581 | — |
| Product | HCID 24756897 | HCID 24756897 | 50% |
Reaction Steps
The title compound was synthesized in analogy to example 46, intermediate e), from 2-(morpholine-4-carbonyl)-1-(2,2,2-trifluoro-ethyl)-1H-indole-5-carboxylic acid and 1-cyclobutylpiperazine (commercially available), to give the desired product as a white solid (50%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601711B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-26f0eb8265054edea7399be73716444c |
| Source note | uspto-grants-2009_10 |