HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 86615806, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Bromomethylcyclopropane | HCID 81503 | — |
| Reactant | HCID 86615807 | HCID 86615807 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86615806 | HCID 86615806 | 40% |
Reaction Steps
The title compound was synthesized in analogy to example 51, from 5-(4-isopropyl-piperazine-1-carbonyl)-1H-indole-2-carboxylic acid (3-fluoro-oxetan-3-ylmethyl)-amide, sodium hydride and cyclopropylmethyl bromide in N,N-dimethylformamide, to give the desired product as a colorless foam (40%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601711B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-466490ab683043a09b55204c885a37e1 |
| Source note | uspto-grants-2009_10 |