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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1820437Generated: October 27, 2026

Benzene, 1-iodo-4-(trifluoromethyl)- → [5-(4-Isopropyl-piperazine-1-carbonyl)-1-(4-trifluoromethyl-phenyl)-1h-indol-2-yl]-morpholin-4-yl-methanone

https://huagongshe.com/reaction/1820437

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-iodo-4-(trifluoromethyl)-HCID 67993—
Reactant[5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-morpholin-4-yl-methanoneHCID 68683056—
Product[5-(4-Isopropyl-piperazine-1-carbonyl)-1-(4-trifluoromethyl-phenyl)-1h-indol-2-yl]-morpholin-4-yl-methanoneHCID 68682850—

Reaction Steps

The title compound was synthesized in analogy to example 116, from [5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-morpholin-4-yl-methanone and 4-iodobenzotrifluoride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07601711B2
Source datasetuspto-grants-2009_10
ORD IDord-608b3a4cfe384e479d15d73cb57c665d
Source noteuspto-grants-2009_10