HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetonitrile → HCID 68681548, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 68683127 | HCID 68683127 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 68681548 | HCID 68681548 | 7% |
Reaction Steps
The title compound was synthesized in analogy to example 51, from [5-(4-cyclobutyl-piperazine-1-carbonyl)-1H-indol-2-yl]-(1,1-dioxothiomorpholin-4-yl)-methanone (example 202), sodium hydride and bromoacetonitrile in N,N-dimethylformamide, to give the desired product as a yellow gum (7%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07601711B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-61a15cd9c6364f569b6edc1b6b584f0c |
| Source note | uspto-grants-2009_10 |