HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenol → HCID 69037206, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenol | HCID 9732 | — |
| Reactant | ethyl 2-chloro-5-nitrobenzoate | HCID 2774222 | — |
| Reactant | HCID 16784872 | HCID 16784872 | — |
| Product | HCID 69037206 | HCID 69037206 | — |
Reaction Steps
2-(4-Fluoro-phenoxy)-5-nitro-benzoic acid can be prepared by a similar method to that described in the literature (e.g. WO9938845) by reaction of 2-Chloro-5-nitro-benzoic acid ethyl ester [16588-17-3] with 4-Fluoro-phenol [371-35-7] yielding 2-(4-Fluoro-phenoxy)-5-nitro-benzoic acid ethyl ester. 2-(4-Fluoro-phenoxy)-5-nitro-benzoic acid ethyl ester can then be hydrolysed with sodium hydroxide for example to yield the title compound. MS (m/e): 276.1 (M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07605163B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-5d15c4e8afa344d492706b982c91fcb8 |
| Source note | uspto-grants-2009_10 |