2,6-Difluorobenzoic acid → 3-(Chlorosulfonyl)-2,6-difluorobenzoic acid

Participants

Reaction Steps

95 mmol of 2,6-difluorobenzoic acid in 19 ml of chlorosulfonic acid was stirred for 2 h at 150°. The mixture was poured into 200 ml of ice and stirred for 20 min. The resulting slurry was filtered, washed with water and dried (20° overnight in the dessicator) to yield the title compound as a colorless solid. MS (m/e): 279.4 (MNa+, 81%)

Provenance & Evidence