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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1820746Generated: October 31, 2026

tert-Butyl piperazine-1-carboxylate → 4-[4-(2-Methyl-2H-tetrazol-5-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1820746

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
Reactant2-Methyl-5-(4-bromophenyl)tetrazoleHCID 610977—
Product4-[4-(2-Methyl-2H-tetrazol-5-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl esterHCID 69038486—

Reaction Steps

Prepared in analogy to example 4.4(a) from 5-(4-Bromo-phenyl)-2-methyl-2H-tetrazole and N-BOC-piperazine. MS (m/e): 345.1 (MH+, 41%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07605163B2
Source datasetuspto-grants-2009_10
ORD IDord-d53201c424664f8f964034936abd25b0
Source noteuspto-grants-2009_10