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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1820747Generated: October 31, 2026

Hydrochloric Acid → 1-[4-(2-Methyl-2H-tetrazol-5-yl)-phenyl]-piperazine hydrochloride

https://huagongshe.com/reaction/1820747

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant4-[4-(2-Methyl-2H-tetrazol-5-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl esterHCID 69038486—
Solvent1,4-DioxaneHCID 31275—
Product1-[4-(2-Methyl-2H-tetrazol-5-yl)-phenyl]-piperazine hydrochlorideHCID 69040865—

Reaction Steps

Prepared in analogy to example 4.4(b) from 4-[4-(2-Methyl-2H-tetrazol-5-yl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester and hydrochloric acid in dioxane. MS (m/e): 245.1 (MH+, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07605163B2
Source datasetuspto-grants-2009_10
ORD IDord-265ef415e9ad403c98433de2c52df93b
Source noteuspto-grants-2009_10