2,6-Difluorobenzoic acid → 3-(Chlorosulfonyl)-2,6-difluorobenzoic acid

Participants

Reaction Conditions

Reaction Steps

77 mmol of 2,6-difluorobenzoic acid were dissolved in 15.5 ml of chlorosulfonic acid and stirred for 2 h at 150° C. The reaction mixture was cooled to room temperature and poured into 100 ml of ice/water. The solid was filtered and dried to yield the title compound as a colorless solid. MS (m/e): 255.1 (M−H, 44%)

Provenance & Evidence