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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1820774Generated: October 25, 2026

Sodium cyclopentanolate → (6-Cyclopentyloxy-2-fluoro-3-methanesulfonyl-phenyl)-[4-(2-fluoro-4-methanesulfonyl-phenyl)-piperazin-1-yl]-methanone

https://huagongshe.com/reaction/1820774

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium cyclopentanolateHCID 23691861—
Reactant(2,6-Difluoro-3-methanesulfonyl-phenyl)-[4-(2-fluoro-4-methanesulfonyl-phenyl)-piperazin-1-yl]-methanoneHCID 69037451—
Product(6-Cyclopentyloxy-2-fluoro-3-methanesulfonyl-phenyl)-[4-(2-fluoro-4-methanesulfonyl-phenyl)-piperazin-1-yl]-methanoneHCID 69042150—

Reaction Steps

The compound was prepared in analogy to example 358 from (2,6-difluoro-3-methanesulfonyl-phenyl)-[4-(2-fluoro-4-methanesulfonyl-phenyl)-piperazin-1-yl]-methanone and sodium cyclopentanolate. MS (m/e): 560.5 (MNH4+, 43%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07605163B2
Source datasetuspto-grants-2009_10
ORD IDord-225b150c256c4c458d9348aabb253408
Source noteuspto-grants-2009_10