HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitro-2-(trifluoromethyl)pyridine 1-oxide → 1-(2-(Trifluoromethyl)Pyridin-4-Yl)Piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitro-2-(trifluoromethyl)pyridine 1-oxide | HCID 10352991 | — |
| Reactant | 4-Bromo-2-methyl-6-(trifluoromethyl)pyridine | HCID 57351538 | — |
| Product | 1-(2-(Trifluoromethyl)Pyridin-4-Yl)Piperazine | HCID 69037547 | — |
Reaction Steps
The compound can be prepared from 4-Nitro-2-trifluoromethyl-pyridine 1-oxide [147149-97-1] in analogy to the procedure used for the preparation of 4-Bromo-2-methyl-6-trifluoromethyl-pyridine [615579-78-1] (WO03087056). MS (m/e): 227 (M+H+, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07605163B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-ceae6b3969a34e699ec30894631e8e4a |
| Source note | uspto-grants-2009_10 |