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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1820830Generated: October 25, 2026

Bromocyclopropane → (2-Allyloxy-5-nitro-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone

https://huagongshe.com/reaction/1820830

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromocyclopropaneHCID 78037—
Reactant(2-Hydroxy-5-nitro-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanoneHCID 69036826—
Product(2-Allyloxy-5-nitro-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanoneHCID 69036586—

Reaction Steps

The title compound was prepared in analogy to example 62 from (2-Hydroxy-5-nitro-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone (compound 2.1) and cyclopropyl bromide. MS (m/e): 436.5 (MH+, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07605163B2
Source datasetuspto-grants-2009_10
ORD IDord-32070ec13fd1435bbf8869de98ec2c60
Source noteuspto-grants-2009_10