HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazine → (2-Benzyloxy-5-methanesulfonyl-phenyl)-[4-(3-fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazine | HCID 44184874 | — |
| Reactant | 2-Benzyloxy-5-methanesulfonyl-benzoic acid | HCID 68826683 | — |
| Product | (2-Benzyloxy-5-methanesulfonyl-phenyl)-[4-(3-fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-methanone | HCID 69042385 | — |
Reaction Steps
The title compound was prepared in analogy to example 5 from 1-(3-Fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazine (compound 5.5) and 2-Benzyloxy-5-methanesulfonyl-benzoic acid (compound 7.5). MS (m/e): 538.4 (MH+, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07605163B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-78bac1b5e5e6420ebd062242c89d7c7d |
| Source note | uspto-grants-2009_10 |