HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenyl Isocyanate → 3-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolo[2,3-b]pyridine-1-carboxylic acid (3-nitro-4-fluoro-phenyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| Reactant | 4-Fluoro-3-nitrophenyl isocyanate | HCID 144117 | — |
| Reactant | 3-[3-(Cyclopentyloxy)-4-methoxyphenyl]-1H-pyrrolo[2,3-b]pyridine | HCID 57891676 | — |
| Product | 3-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolo[2,3-b]pyridine-1-carboxylic acid (3-nitro-4-fluoro-phenyl)-amide | HCID 57891771 | — |
Reaction Steps
3-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolo[2,3-b]pyridine-1-carboxylic acid (3-nitro-4-fluoro-phenyl)-amide 98 was prepared using the same protocol as described in Example 25, substituting 3-(3,4-dimethoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine 1 and 4-chlorophenyl isocyanate with 3-(3-Cyclopentyloxy-4-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine 88 and 4-fluoro-3-nitrophenyl isocyanate respectively. MS(ESI) [M+H+]+=491.10.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07605168B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-8de5a8bde3b445b9a4df8ad9f79d3ad3 |
| Source note | uspto-grants-2009_10 |