HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(3,4-dimethoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine → [3-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolo[2,3-b]pyridin-1-yl]-[2-(2,2,2-trifluoro-ethoxy)-naphthalen-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(3,4-dimethoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine | HCID 11673285 | — |
| Reactant | 2-(2,2,2-Trifluoro-ethoxy)-naphthalene-1-carboxylic acid | HCID 43505614 | — |
| Reactant | 3-[3-(Cyclopentyloxy)-4-methoxyphenyl]-1H-pyrrolo[2,3-b]pyridine | HCID 57891676 | — |
| Product | [3-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolo[2,3-b]pyridin-1-yl]-[2-(2,2,2-trifluoro-ethoxy)-naphthalen-1-yl]-methanone | HCID 57891726 | — |
Reaction Steps
[3-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolo[2,3-b]pyridin-1-yl]-[2-(2,2,2-trifluoro-ethoxy)-naphthalen-1-yl]-methanone 124 was prepared using the same protocol as described in Example 47, substituting 2-ethoxy-4-nitro-benzoic acid and 3-(3,4-Dimethoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine with 2-(2,2,2-Trifluoro-ethoxy)-naphthalene-1-carboxylic acid and 3-(3-cyclopentoxy-4-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine. MS(ESI) [M+H+]+=561.10.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07605168B2 |
| Source dataset | uspto-grants-2009_10 |
| ORD ID | ord-02950d1733bb4aa38d1fc2e6a9354450 |
| Source note | uspto-grants-2009_10 |