1-Dodecanethiol → Sodium dodecane-1-thiolate

HRID 1821152Notes

Reaction equation

HRID 1821152 reaction equation
C[O-].[Na+:3].[CH2:4]([SH:16])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]>CO>[CH2:4]([S-:16])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15].[Na+:3]

Participants

4

Reactant 2

HCID 81951-DodecanethiolHCID 10942334Sodium Methoxide

Product 1

HCID 23672953Sodium dodecane-1-thiolate

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In another flask, sodium methoxide (8.1 g, 150 mmol) was dissolved in 10 ml methanol, and dodecanethiol (32.8 ml, 136.6 mmol) was added. The resulting solution was stirred at room temperature for 15 minutes. The solvent was then evaporated under reduced pressure at 90° C. Traces of methanol were evaporated by adding toluene and evaporating it at reduced pressure at 100° C. for two hours.

Workup

  1. customThe solvent was then evaporated under reduced pressure at 90° C
  2. customTraces of methanol were evaporated
  3. additionby adding toluene
  4. customevaporating it at reduced pressure at 100° C. for two hours

Sources & evidence

ORD record
ord-e41c66d3f40a4b99b2fc39857ea29e64
Source dataset
uspto-grants-2009_10
Patent number
US07605290B2

Reaction notes

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