HRID1821204

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8022

Ethyl isocyanate

C3H5NO

结构：CCn1cc(-c2ccnc3[nH]c(-c4ccc(CN(C)C)cc4)cc23)c(-c2ccc(N)cc2)n1

HCID68998028

未命名化合物

PRODUCTS

生成物

结构：CCNC(=O)Nc1ccc(-c2nn(CC)cc2-c2ccnc3[nH]c(-c4ccc(CN(C)C)cc4)cc23)cc1

HCID24816055

未命名化合物

PROCEDURE

实验过程

Following the procedure described in Example 48 using 4-[3-(4-aminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[4-(dimethylaminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridine and ethyl isocyanate provided the title compound. ESMS (M+H)+: 508.4

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5cbcf287121040e5b230ad6296043719
来源数据集: uspto-grants-2009_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07605266B2
来源说明: uspto-grants-2009_10

反应 SMILES

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:12]([C:13]3[CH:18]=[CH:17][N:16]=[C:15]4[NH:19][C:20]([C:22]5[CH:27]=[CH:26][C:25]([CH2:28][N:29]([CH3:31])[CH3:30])=[CH:24][CH:23]=5)=[CH:21][C:14]=34)=[CH:11][N:10]([CH2:32][CH3:33])[N:9]=2)=[CH:4][CH:3]=1.[CH2:34]([N:36]=[C:37]=[O:38])[CH3:35]>>[CH3:35][CH2:34][NH:36][C:37]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:12]([C:13]3[CH:18]=[CH:17][N:16]=[C:15]4[C:14]=3[CH:21]=[C:20]([C:22]3[CH:27]=[CH:26][C:25]([CH2:28][N:29]([CH3:30])[CH3:31])=[CH:24][CH:23]=3)[NH:19]4)=[CH:11][N:10]([CH2:32][CH3:33])[N:9]=2)=[CH:6][CH:7]=1)=[O:38]