2-Morpholinoethylamine → 4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-N-[2-(4-morpholinyl)ethyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	2-Morpholinoethylamine	HCID 408285	—
Reactant	4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid	HCID 46236484	—
Product	4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-N-[2-(4-morpholinyl)ethyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide	HCID 46236619	—

Reaction Steps

Following the procedure described in Example 15a using 4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid and 4-(2-aminoethyl)-morpholine afforded the title compound. ESMS [M+H]+: 490.4

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07605266B2
Source dataset	uspto-grants-2009_10
ORD ID	ord-b4688d5497f441f1a166b9644b9a2208
Source note	uspto-grants-2009_10