Sodium ion → N-cyclopropyl-3-(8-(2,4-difluorophenyl)-1-methyl-2-oxo-1,2-dihydropyrido(3,2-d)pyridazin-3-yl)-4-methylbenzamide
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][n:6][n:7][c:8](-[c:14]3[c:15]([F:21])[cH:16][c:17]([F:20])[cH:18][cH:19]3)[c:9]2[n:10]([CH3:13])[c:11]1=[O:12].[C:28](=[O:29])([O-:30])[O-:31].[CH2:22]1[O:23][CH2:24][CH2:25][O:26][CH2:27]1.[CH:34]1([NH:37][C:38]([c:39]2[cH:40][c:41]([B:46]3[O:47][C:48]([CH3:49])([CH3:50])[C:51]([CH3:52])([CH3:53])[O:54]3)[c:42]([CH3:45])[cH:43][cH:44]2)=[O:55])[CH2:35][CH2:36]1.[Na+:32].[Na+:33].[OH2:56].[cH:57]1[cH:58][cH:59][c:60]([P:61]([Pd:62]([P:63]([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)([P:82]([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)([c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[P:101]([c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)([c:108]2[cH:109][cH:110][cH:111][cH:112][cH:113]2)[c:114]2[cH:115][cH:116][cH:117][cH:118][cH:119]2)([c:120]2[cH:121][cH:122][cH:123][cH:124][cH:125]2)[c:126]2[cH:127][cH:128][cH:129][cH:130][cH:131]2)[cH:132][cH:133]1>>[c:2]1(-[c:41]2[cH:40][c:39]([C:38]([NH:37][CH:34]3[CH2:35][CH2:36]3)=[O:55])[cH:44][cH:43][c:42]2[CH3:45])[cH:3][c:4]2[cH:5][n:6][n:7][c:8](-[c:14]3[c:15]([F:21])[cH:16][c:17]([F:20])[cH:18][cH:19]3)[c:9]2[n:10]([CH3:13])[c:11]1=[O:12]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-11930ce821404ae0a43a4391aaf8d427
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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