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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1821286Generated: November 1, 2026

1-(1-methylethyl)-3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole → 4-[4-[1-(1-methylethyl)-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-indol-2-yl]benzaldehyde

https://huagongshe.com/reaction/1821286

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(1-methylethyl)-3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 68996616—
Reactant4-[4-bromo-1-(phenylsulfonyl)-1H-indol-2-yl]benzaldehydeHCID 86613324—
Product4-[4-[1-(1-methylethyl)-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-indol-2-yl]benzaldehydeHCID 86613326—

Reaction Steps

Following the procedure for Intermediate 100 using 4-[4-bromo-1-(phenylsulfonyl)-1H-indol-2-yl]benzaldehyde and 1-(1-methylethyl)-3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole provided the title compound. ESMS [M+H]+: 592.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07605266B2
Source datasetuspto-grants-2009_10
ORD IDord-2d2bcd65728244a59df72d90892ae1ea
Source noteuspto-grants-2009_10