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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1821308Generated: November 3, 2026

1-Methylpiperazine → 5-Bromo-2-(4-methylpiperazin-1-yl)pyrimidine

https://huagongshe.com/reaction/1821308

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant5-Bromo-2-chloropyrimidineHCID 606665—
Product5-Bromo-2-(4-methylpiperazin-1-yl)pyrimidineHCID 4128158—

Reaction Steps

Following the procedure described for Intermediate 234 using 5-bromo-2-chloropyrimidine and N-methylpiperazine provided the title compound. ESMS [M+H]+: 257.0/259.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07605266B2
Source datasetuspto-grants-2009_10
ORD IDord-68016abce6b74cb8b0d87531fafd49df
Source noteuspto-grants-2009_10