Water → HCID 69002677, compound

Participants

Reaction Steps

(E)-4-formyl-N-{2-[2-(1H-indazol-3-yl)vinyl]phenyl}benzamide (100 mg, 0.27 mmol) was dissolved in methanol (1.1 mL) and the solution was added with sodium borohydride (120 mg, 2.72 mmol), stirred at room temperature for 1 hour, added with water and extracted with ethyl acetate. The organic layer was sequentially washed with water and saturated brine, dried over anhydrous magnesium sulfate and the solvent was evaporated under reduced pressure. The residue was triturated in ethanol to obtain Compound 79 (10 mg, 10%).

Provenance & Evidence