Hydrochloride methanol → HCID 68998257, compound

HRID 1821337Notes

Reaction equation

HRID 1821337 reaction equation
[CH2:1]([N:3]([CH2:32][CH3:33])[C:4]([C:6]1[CH:7]=[CH:8][C:9](/[CH:21]=[CH:22]/[C:23]2[C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[NH:25][N:24]=2)=[C:10]([NH:12][C:13]([C:15]2[S:16][CH:17]=[CH:18][C:19]=2[CH3:20])=[O:14])[CH:11]=1)=[O:5])[CH3:2].[ClH:34].CO>CO>[ClH:34].[CH2:32]([N:3]([CH2:1][CH3:2])[C:4]([C:6]1[CH:7]=[CH:8][C:9](/[CH:21]=[CH:22]/[C:23]2[C:31]3[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=3)[NH:25][N:24]=2)=[C:10]([NH:12][C:13]([C:15]2[S:16][CH:17]=[CH:18][C:19]=2[CH3:20])=[O:14])[CH:11]=1)=[O:5])[CH3:33]

Participants

4

Reactant 2

HCID 21893726Hydrochloride methanolHCID 68996679HCID 68996679, compound

Product 1

HCID 68998257HCID 68998257, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a similar manner to Example 115, Compound 124 (370 mg, 76%) was obtained from Compound 101, methanol (6.0 mL) and 4 mol/L hydrogen chloride-methanol solution (2.00 mL).

Sources & evidence

ORD record
ord-9d3d3b3cc1b943e6b05c107cb8ba6af3
Source dataset
uspto-grants-2009_10
Patent number
US07605272B2

Reaction notes

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